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Birth Control Pills (Oral Contraceptives)

What are birth control pills, and what are they used for?

Oral contraceptives (birth control pills) are medications that prevent pregnancy. They are one method of birth control.

Oral contraceptives are hormonal preparations that may contain combinations of the hormones estrogen and progestin or progestin alone. Combinations of estrogen and progestin prevent pregnancy by inhibiting the release of the hormones luteinizing hormone (LH) and follicle stimulating hormone (FSH) from the pituitary gland in the brain.

LH and FSH play key roles in the development of the egg and preparation of the lining of the uterus for implantation of the embryo. Progestin also makes the uterine mucus that surrounds the egg more difficult for sperm to penetrate and, therefore, for fertilization to take place. In some women, progestin inhibits ovulation (release of the egg).

3 birth control types

There are different types of combination birth control pills that contain estrogen and progestin that are referred to as monophasic, biphasic, or triphasic.

  • Monophasic birth control pills deliver the same amount of estrogen and progestin every day.
  • Biphasic birth control pills deliver the same amount of estrogen every day for the first 21 days of the cycle. During the second half of the cycle, the progestin/estrogen ratio is higher to allow the normal shedding of the lining of the uterus to occur.
  • Triphasic birth control pills have constant or changing estrogen concentrations and varying progestin concentrations throughout the cycle. There is no evidence that bi- or triphasic oral contraceptives are safer or superior to monophasic oral contraceptives, or vice versa, in their effectiveness for the prevention of pregnancy.

What are the side effects of birth control pills?

The most common side effects of the birth control pills include;

  1. nausea,
  2. headache,
  3. breast tenderness,
  4. weight gain,
  5. irregular vaginal bleeding, and
  6. mood changes.

These side effects often subside after a few months of use.

Scanty menstrual periods or breakthrough bleeding may occur but are often temporary, and neither side effect is serious.

Women with a history of migraines may notice an increase in migraine frequency. On the other hand, women whose migraines are triggered by fluctuations in their own hormone levels may notice improvement in migraines with oral contraceptive use because of the more uniform hormone levels during oral contraceptive use.

Rarely, oral contraceptives may contribute to;

  1. increased blood pressure,
  2. blood clots,
  3. heart attack, and
  4. stroke.

Women who smoke, especially those over 35, and women with certain medical conditions, such as a history of blood clots or breast or endometrial cancer, may be advised against taking oral contraceptives, as these conditions can increase the adverse risks of oral contraceptives.

This is not a complete list of all side effects or adverse reactions that may occur from the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may also report side effects or health problems to the FDA at 1-800-FDA-1088.

List of birth control pill brands and generic names

List of examples of oral contraceptives of different brands and categories:

Alesse-28ethinyl estradiollevonorgestrel
Apriethinyl estradioldesogestrel
Avianeethinyl estradiollevonorgestrel
Breviconethinyl estradiolnorethindrone
Demulen 1/35-21
Demulen 1/35-28
Demulen 1/50-21
Demulen 1/50-28
ethinyl estradiolethynodiol diacetate
Desogenethinyl estradioldesogestrel
Genora 1/35ethinyl estradiolnorethindrone
Genora 1/50mestranolnorethindrone
Levlite 28ethinyl estradiollevonorgestrel
Levlen 21
Levlen 28
ethinyl estradiollevonorgestrel
Levora 0.15/30-21
Levora 0.15/30-28
ethinyl estradiollevonorgestrel
Loestrin 21 1/20
Loestrin 21 1.5/30
Loestrin FE 1/20
Loestrin FE 1.5/30
ethinyl estradiolnorethindrone acetate
Lo-Ovral 28
Ovral 28
ethinyl estradiolnorgestrel
Low-Ogestrel 28
Ogestrel 0.5/50-28
ethinyl estradiolnorgestrel
Microgestin 1/20
Microgestin 1.5/30
Microgestin FE 1/20
Microgestin FE 1/5/30
ethinyl estradiolnorethindrone acetate
Modiconethinyl estradiolnorethindrone
Necon 0.5/35-21
Necon 0.5/35-28
Necon 1/50-21
Necon 1/50-28
Necon 1/35-21
Necon 1/35-28
ethinyl estradiolnorethindrone
Nordette 28ethinyl estradiollevonorgestrel
Norinyl 1/50mestranolnorethindrone
Norinyl 1/35ethinyl estradiolnorethindrone
Nortrel 0.5/35
Nortrel 1/35
ethinyl estradiolnorethindrone
Ortho-Ceptethinyl estradioldesogestrel
Ortho-Novum 1/35ethinyl estradiolnorethindrone
Ortho-Novum 1/50mestranolnorethindrone
Ortho-Cyclenethinyl estradiolnorgestimate
Ovcon 50
Ovcon 35
ethinyl estradiolnorethindrone
Tri-Norinyl 28ethinyl estradiolnorethindrone
Yasmin 28ethinyl estradioldrospirenone
Zovia 1/50E
Zovia 1/35E
ethinyl estradiolethynodiol diacetate
Jenest 28ethinyl estradiolnorethindrone
Mircetteethinyl estradioldesogestrel
Necon 10/11-21
Necon 10/11-28
ethinyl estradiolnorethindrone
Ortho-Novum 10/11ethinyl estradiolnorethindrone
Estrostep 21
Estrostep FE
ethinyl estradiolnorethindrone
Ortho-Novum 7/7/7ethinyl estradiolnorethindrone
Ortho Tri-Cyclen
Ortho Tri-Cyclen LO
ethinyl estradiolnorgestimate
Tri-Levlen 21
Tri-Levlen 28
ethinyl estradiollevonorgestrel
Tri-Norinyl 28ethinyl estradiolnorethindrone
Triphasil 28ethinyl estradiollevonorgestrel
Trivora 28ethinyl estradiollevonorgestrel
24-4 PREPARATIONS (24 days of hormone pills and 4 days of placebo pills)
Yazethinyl estradioldrospirenone
Lo Estrin 24-4ethinyl estradiolnorethindrone acetate
Seasonaleethinyl estradiollevonorgestrel
Seasoniqueethinyl estradiollevonorgestrel

Previous contributing medical author: Carolyn Janet Crandall, MD, MS, FACP



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What is the dosage for birth control pills? How do you take them?

Many of the birth control pills come in easy-to-use dispensers in which the day of the week or a consecutive number (1, 2, 3, etc.) is written on the dispenser with a corresponding tablet for each day or number.

  • For example, some Ortho-Novum dispensers are labeled “Sunday” next to the first tablet. Thus, the first tablet is to be taken on the first Sunday after menstruation begins (the first Sunday following the first day of a woman’s period). If her period begins on Sunday, the first tablet should be taken on that day.
  • For birth control pills that use consecutive numbers, the first tablet (#1) is taken on the first day of the menstrual period (the first day of bleeding). Tablet #2 is taken on the second day and so on.
  • Still other packages instruct women to begin on day five of the cycle. For such products, women count from day one of their menstrual cycle (day one is the first day of bleeding). On the fifth day, the first tablet is taken. Tablets then are taken daily.
  • Most birth control pills are packaged as 21-day or 28-day units. For 21-day packages, tablets are taken daily for 21 days. This is followed by a seven-day period during which no birth control pills are taken. Then the cycle repeats.
  • For the 28-day units, tablets containing medication are taken for 21 consecutive days, followed by a seven-day period during which placebo tablets (containing no medication) are taken.
  • Newer formulations with 24 days of hormone pills and only four days of placebo pills are now available, as are continuous or extended-cycle oral contraceptive regimens, in which only active hormone pills are taken. Extended-cycle preparations include seven-day intervals of placebo pills to be taken approximately every three months.
  • Women just starting to take birth control pills should use additional contraception for the first seven days of use because pregnancy may occur during this period.
  • If women forget to take tablets, pregnancy may result. If a single tablet is forgotten, it should be taken as soon as it is realized that it is forgotten. If more than one tablet is forgotten, the instructions that come with the packaging should be consulted, or a physician or pharmacist should be called.

Health News

What drugs interact with birth control pills?

Estrogens can inhibit the metabolism (elimination) of cyclosporine, resulting in increased cyclosporine blood levels. Such increased blood levels can result in kidney and/or liver damage. If this combination cannot be avoided, cyclosporine concentrations can be monitored, and the dose of cyclosporine can be adjusted to assure that its blood levels do not become elevated.

Estrogens appear to increase the risk of liver disease in patients receiving dantrolene (Dantrium) through an unknown mechanism. Women over 35 years of age and those with a history of liver disease are especially at risk.

Estrogens increase the liver’s ability to manufacture clotting factors. Because of this, patients receiving warfarin (Coumadin) need to be monitored for loss of anticoagulant (blood thinning) effect if an estrogen is begun.

Several medications, including some antibiotics and antiseizure medications, can decrease the blood levels of oral contraceptive hormones, but an actual decrease in the effectiveness of the oral contraceptive has not been convincingly proven. Nonetheless, because of this theoretical possibility, some physicians recommend backup contraceptive methods during antibiotic use. Examples of medications that increase the elimination of estrogens include

Birth control pills with higher concentrations of estrogen or alternative forms of contraception may be necessary in women using those medications.

Are birth control pills safe to take if you are breastfeeding?

Use of birth control pills during lactation has been associated with decreased milk production, decreased infant weight gain, and decreased nitrogen and protein content of milk. The amount of estrogen consumed by an infant whose mother takes a standard dose of birth control pills is considered to be the same as from a lactating woman who is not taking birth control pills, and side effects have not been reported.

Using a progestin-only product is most often recommended during lactation if birth control pills are to be used during this period. The American College of Obstetrics and Gynecology (ACOG) recommends delaying taking combined estrogen-progestin contraceptives until at least six weeks postpartum, while the World Health Organization (WHO) recommends delaying the initiation of combined contraceptives until six months.

How do you store birth control pills safely?

  • All oral contraceptives should be stored in a safe place, out of the reach of small children, at a temperature between 15 C (59 F) and 30 C (86 F).

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Medically Reviewed on 6/29/2022


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